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GitHub is home to over 36 million developers working together to host and review code, manage projects, and build software together. Recently, mutations or high expression of the familial predisposition gene Anaplastic Lymphoma Kinase ALK was associated to unfavourable biology of sporadic NB. Also, various other genes have been linked to NB pathogenesis. Results The present study explores subgroup discrimination by gene expression profiling using three published microarray studies on NB 47 samples. Four distinct clusters were identified by Principal Components Analysis PCA in two separate data sets, which could be verified by an unsupervised hierarchical clustering in a third independent data set NB samples using a set of 74 discriminative genes.
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